Liquid biopsies are tests that detect signs of cancer through a simple blood draw. Unlike traditional biopsies, which require removing a piece of tissue, a liquid biopsy typically looks for mutations ...

Liquid biopsies have transformed cancer testing. These tests detect signs of cancer using a simple blood draw instead of removing tissue from the body. Traditional biopsies involve surgery, needles, ...

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...

Genome editing is a powerful biotechnology tool that allows scientists to make precise changes to an organism's DNA. It involves the use of specialized enzymes, known as engineered nucleases or ...

Modern crop breeding is entering a new era of genome design, led by genome editing technologies as mainstream tools for targeted genome modification. In a review published in Nature Reviews Genetics, ...

An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene ...

DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...

The discovery of CRISPR-Cas9’s gene-editing prowess revolutionized genetic engineering just over a decade ago. Now it appears that genetic engineering technology may be taking its next big leap.

A new study has created a map of DNA modification in two regions of the brain critical to learning, memory and emotional regulation. The map offers a benchmark for ensuring stem cell-based models ...