NOTCH1 mutations, found in 20% of CLL cases, are associated with poor outcomes in chemotherapy but not yet in treatment guidelines. A retrospective analysis showed improved PFS for NOTCH1-mutated CLL ...

A new study by researchers at the Icahn School of Medicine at Mount Sinai, Memorial Sloan Kettering Cancer Center, and collaborators, suggests that artificial intelligence (AI) could significantly ...

Abstract: Mutation testing aims to simulate real-world defects, but existing tools often struggle to replicate method invocation defects accurately. To address this, we propose MIN (Method INvocation ...

Blood-based circulating tumor DNA (ctDNA) testing has proven to be insufficient for detecting KRAS mutations in patients with low-grade serous ovarian cancer (LGSOC), according to a study. The ...

A new blood test will be offered to lung cancer patients in a move that NHS England says will benefit about 15,000 people each year. The test, known as a liquid biopsy, is designed to speed up access ...

ST. PAUL, Minn., May 25 (UPI) --A new rapid blood test for newborns could potentially detect genetic mutations linked to thousands of rare diseases all at once, greatly improving on current ...

The illustration of protein structure (domains) on the left side, and corresponding exons in the FLT3 gene are displayed on the right side. FMS-like tyrosine kinase 3 (FLT3) mutations represent some ...

Panelists discuss how to approach second-line therapy decisions for patients with metastatic breast cancer, emphasizing the importance of biomarker testing, including ESR1 mutations, and considering ...

Testing made easy with Azure DevOps! In this session, learn how to create, manage, and track test plans to boost quality and streamline your development workflow. The US government seems to have a ...

This Reading Room is a collaboration between MedPage Today® and: Patients who had genetic testing for BRCA mutations prior to breast cancer diagnosis had smaller tumors, less nodal involvement, and ...